Tryfonia is L-5-hydroxytryptophan (5-HTP) derived from Griffonia simplicifolia seed extract. 5-HTP is a metabolite of the amino acid tryptophan, and an essential precursor of the neurotransmitter serotonin and the neurohormone melatonin. Collectively, 5-HTP, serotonin and melatonin are important for the regulation of mood and healthy sleep.

5-HTP is primarily used to support mood through its ability to boost serotonin levels. 5-HTP has been compared to various tricyclic antidepressants and has been found to be as effective with fewer side effects and quicker effectiveness. Since serotonin and melatonin are also involved in regulating the sleep wake cycle, 5-HTP may enhance sleep quality. Research also supports a role for 5-HTP in reducing headaches and the symptoms of fibromyalgia. Studies in Spain and Italy found that 5-HTP was comparable to the drug methysergide in alleviating the symptoms of migraines (over 70% in both groups) while eliciting considerably fewer side effects. Fibromyalgia patients have been found to have low serotonin levels and have shown symptomatic improvement with the use of tricyclic and SSRI antidepressants. Several clinical trials have confirmed significant improvements in symptoms, including pain, morning stiffness, nervousness, and fatigue.  Ultimately, those who suffer with nervousness, mood imbalances such as anxiety, fibromyalgia or sleep disorders may benefit from taking 5-HTP. Tryfonia MAX is twice the strength of regular Tryfonia.