D-Mannose and Cranberry is formulated with therapeutic proportions of three proven natural ingredients. D Mannose is a simple naturally-occurring sugar that is not converted to glycogen in the liver; it enters the blood stream directly, and upon exposure within the kidney, it attaches to Escherichia coli bacteria for harmless excretion. The effectiveness of D-Mannose and Cranberry is reflected by the fact that approximately eighty percent of UTIs result from infections caused by E. coli.

D-Mannose and Cranberry also contains proanthocyanidin-rich cranberry (107× concentrate). Proanthocyanidins prevent the adherence of E. coli within the entire urinary tract. The probiotic Lactobacillius rhamnosus included in D-Mannose and Cranberry is a specialized probiotic strain recognized for its effectiveness with antibiotic-resistant bacterial strains. L. rhamnonus is extremely resistant to stomach acids, and produces compounds (surfactants) that disrupt pathogenic bacterial strains from adhering to the lining of the urinary tract.